Cases per person-years were 0.06 in orchestras, 0.11 in choirs, and 0.03 in controls. In 1,097 participants (46.7 years (SD 10.3) 46.8% female 705 orchestra, 154 choir, and 238 control subjects) 40 SARS-CoV-2 infections occurred. A mixed-effects cox proportional hazards model was used to assess the effect of exposure by professional activity on SARS-CoV-2 infection. Data were collected from October 2020 to June 2021 by weekly online surveys. Musicians from professional orchestras and choirs and controls from 23 institutions throughout Germany were included in a prospective cohort study. We also assessed influenza, flu, upper respiratory tract infections, and course of illness. Therefore, our primary objective was to determine the incidence of SARS-CoV-2 infections in orchestra and choir musicians compared to controls. During the COVID-19 pandemic, rehearsal and concert activities of professional orchestras and choirs were severely restricted based on the assumption of particularly high infection risks associated with wind instruments and singing.
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